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What is hyperlipidemia, one of the "three high", and what is its harm?

   2023-03-01

We often hear doctors say to be careful"Three high" and "three high" are not a disease, but a combination of "high blood pressure, high blood sugar and high blood fat".

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People pay more and more attention to hypertension and hyperglycemia. Hypertension will lead to cerebral hemorrhage, cerebral infarction and other diseases, and hyperglycemia will lead to diabetes, which will lead to vascular blockage, kidney disease and bad feet……

So what is hyperlipidemia, which is parallel to hypertension and hyperglycemia? What are the hazards?

IWhat is blood fat?

Blood fat is the general name of lipid substances in the blood, but it usually refers to total blood cholesterol (abbreviated asTC) and triglyceride (TG).

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They are the main source of heat energy for the human body, constitute the basic raw material for cells, and also participate in the synthesis of hormones and other important life substances in the body. They are one of the essential nutrients for the human body. They mainly come from food, and a small part is produced in the metabolism process of our body.

The absorption, production, consumption and transformation of lipids in normal human body maintain dynamic balance. Lipids are insoluble in water and combine with proteins to form lipoproteins, which circulate in the blood.

IIGood and bad cholesterol

Cholesterol is also divided into low density lipoprotein cholesterol(LDL-C) and high-density lipoprotein cholesterol (HDL-C).

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Low density lipoprotein transports cholesterol from the liver to the whole body. When low density lipoprotein is excessive, the cholesterol it carries will accumulate on the arterial wall, and over time, it will easily lead to arteriosclerosis. Therefore, low density lipoprotein is called"Bad cholesterol".

High-density lipoprotein(HDL) carries cholesterol in surrounding tissues to the liver for metabolism, so high-density lipoprotein is a plasma lipoprotein that can resist atherosclerosis and is a protective factor of coronary heart disease. Therefore, high-density lipoprotein is called "good cholesterol".

IIIDiagnosis of hyperlipidemia

Compared with the total amount of lipids in the body, the content of lipids in the blood only accounts for a small part, but it is transported between tissues, often reflecting the metabolism of lipids in the body.

In China, the total fasting serum cholesterol of adults generally exceeds5.7 mmol/L, triglyceride more than 1.70 mmol/L, can be diagnosed as hyperlipidemia.

IVEtiology of hyperlipidemia

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As for the etiology of hyperlipidemia, some are caused by the interaction of multiple genetic defects and environmental factors, some are caused by high dietary saturated fatty acids, excessive eating, smoking, less exercise, obesity, certain drugs, and some are secondary to other diseases. Therefore, hyperlipemia is not a specific disease, but a group of diseases.

VHyperlipidemia younger

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Hyperlipidemia patients tend to be younger. Generally, the incidence rate of hyperlipidemia tends to increase with ageAdults aged from 45 to 60 years old are the majority, among which there are more young and middle-aged men, and there are also many female patients after middle age. According to the current clinical findings, the incidence of hyperlipidemia in young people is also increasing significantly.

VIHyperlipidemic6 major hazards:

1. Hyperlipidemia can lead to atherosclerosis

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A large number of lipid material proteins deposit and move in the plasma, reduce the blood flow rate, damage the artery endothelium, and form arterial atherosclerosis.

2. Hyperlipidemia can lead to coronary heart disease

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When the human body forms atherosclerosis due to long-term high-fat blood, it causes myocardial ischemia, angina pectoris, and coronary heart disease.

3. High blood fat can cause high blood pressure

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After the formation of atherosclerosis in human blood vessels, it will cause arterial stenosis, myocardial dysfunction, and lead to increased blood pressure.

4. Hyperlipidemia can lead to stroke

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High blood pressure caused by high blood fat will often make blood vessels in spastic state, while the endothelium of cerebral vessels will be damaged after hardening, and the continuous high pressure will lead to blood vessel rupture, forming hemorrhagic cerebral stroke, while the cerebral vessels will stagnate in the state of thrombosis, leading to cerebral thrombosis and cerebral embolism.

5. Hyperlipidemia can cause liver function damage

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Long term hyperlipidemia will lead to fatty liver, and liver atherosclerosis will be damaged, which will lead to cirrhosis and damage liver function.

6. Hyperlipidemia will lead to acidification of human body

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Hyperlipidemia will cause a large number of lipid proteins to dissociate in plasma, which is easily oxidized and rancid, acidifies human body fluid, is vulnerable to infection by viruses and bacteria, and affects the decomposition and dissociation of calcium, leading to calcium deficiency and osteoporosis in the body.